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Zinca-ene-allene and zinc-enolate cyclization. Towards the synthesis of polysubstituted pyrrolidines

โœ Scribed by Edwige Lorthiois; Ilane Marek; Jean-F. Normant


Book ID
104255973
Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
207 KB
Volume
38
Category
Article
ISSN
0040-4039

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โœฆ Synopsis


The synthesis of polysubstituted pyrrolidines can be easily achieved in a diastereoselective and enantioselective way via the zinca-ene-allene and zinc-enolate cyclization.


๐Ÿ“œ SIMILAR VOLUMES


Diastereoselective construction of cis 2
โœ Teck-Peng Loh; Jian-Ying Yang; Li-Chun Feng; Yan Zhou ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 129 KB

Diastereoselective construction of 2,6-disubstituted tetrahydropyrans with an exocyclic double bond was achieved via the In(OTf) 3 -catalyzed intramolecular 2,5-oxonium-ene cyclization. Its application was further demonstrated by the synthesis of a common intermediate for both zampanolide and dactyl