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Zinc-induced anti-apoptotic effects in SH-SY5Y neuroblastoma cells via the extracellular signal-regulated kinase 1/2

✍ Scribed by Wen-Lin An; Jin-Jing Pei; Takeshi Nishimura; Bengt Winblad; Richard F. Cowburn

Book ID
116753265
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
579 KB
Volume
135
Category
Article
ISSN
0169-328X

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Acrylonitrile (ACN) is classified by IARC as a probable carcinogen. Chronic exposure to ACN increases the incidence of tumors in various organs of test animals, including the brain and lung. ERK1/2 activation plays crucial roles in cell proliferation and is involved in many steps of tumor progressio