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Zinc finger proteins: A bridge between transition metals and gene regulation

โœ Scribed by Andrew Green; Maura Parker; Damiano Conte; Bibudhendra Sarkar

Book ID
101299574
Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
143 KB
Volume
11
Category
Article
ISSN
0896-548X

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Amplification and over-expression of OZF
Amplification and over-expression of OZF, a gene encoding a zinc finger protein, in human pancreatic carcinomas
โœ Didier Ferbus; Aude Flรฉchon; Martine Muleris; Yong Li; Samir Hanash; Benoรฎt Terr ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 110 KB ๐Ÿ‘ 2 views

The OZF gene encodes a protein consisting of 10 zinc finger motifs and is located on chromosome 19q13.1. We report here the amplification and over-expression of the OZF gene in pancreatic carcinomas. Increased gene copy number was detected in 3 of 12 tumour cell lines and 2 of 12 primary pancreatic