Zidovudine, Diclofenac and Ketoprofen Pharmacokinetic Interactions in Rats
β Scribed by MAHASEN A. RADWAN
- Book ID
- 111768508
- Publisher
- Pharmaceutical Press
- Year
- 2000
- Tongue
- English
- Weight
- 73 KB
- Volume
- 52
- Category
- Article
- ISSN
- 2042-7158
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π SIMILAR VOLUMES
## Abstract The effects of age and dose on the pharmacokinetics of ketoprofen were evaluated in young adult and senescent male Fischer 344 rats following intravenous administration of 2Β·5 and 10 mg kg^β1^. Plasma concentrations were measured by HPLC and free ketoprofen determined by equilibrium dia
The purpose of this study was to assess the effects of dose on the pharmacokinetics of zidovudine (3'-azido-3'-deoxythymidine; AZT) in rats. Zidovudine (AZT) was administered intravenously at doses of 10, 50, 100, and 250 mgikg. Plasma and urine AZT concentrations were determined by HPLC. Plasma AZT