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Ytterbium Triflate as an Efficient Catalyst for One-Pot Synthesis of Substituted Imidazoles Through Three-Component Condensation of Benzil, Aldehydes and Ammonium Acetate.

โœ Scribed by Li-Min Wang; Yong-Hong Wang; He Tian; Yin-Fang Yao; Jue-Hua Shao; Bo Liu


Publisher
John Wiley and Sons
Year
2007
Weight
21 KB
Volume
38
Category
Article
ISSN
0931-7597

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One-Pot Synthesis of cis-Isoquinolonic A
โœ Limin Wang; Jijun Liu; He Tian; Changtao Qian; Jie Sun ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 92 KB ๐Ÿ‘ 2 views

Ytterbium(III) triflate efficiently catalyzes the one-pot reaction of homophthalic anhydride with aldehydes and amines at ambient temperature to afford the corresponding cis-isoquinolonic acid derivatives in good to excellent yields with high diastereoselectivity. This method provides a novel and mu