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Y-chromosome loss in acute promyelocytic leukemia

✍ Scribed by Yafang Wu; Yongquan Xue; Jinlan Pan

Book ID
113512503
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
137 KB
Volume
157
Category
Article
ISSN
0165-4608

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Y-chromosome loss as the sole karyotypic anomaly with 3β€²RARΞ± submicroscopic deletion in a case of M3r subtype of acute promyelocytic leukemia
✍ Yongsheng Han; Yongquan Xue; Jun Zhang; Jinlan Pan; Yafang Wu; Shuxiao Bai πŸ“‚ Article πŸ“… 2009 πŸ› Elsevier Science 🌐 English βš– 316 KB

Acute promyelocytic leukemia (APL) is characterized by the presence of a chromosomal rearrangement involving retinoic acid receptor alpha (RARalpha) gene generating the X-RARalpha fusion. We describe here a unique RARalpha gene rearrangement in a patient with M3r subtype of APL. Conventional cytogen