Xanthine oxidase inhibitory activity of Chilean Myrtaceae
β Scribed by Theoduloz, Cristina; Pacheco, Patricia; Schmeda-Hirschmann, Guillermo
- Book ID
- 120937131
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 231 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0378-8741
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π SIMILAR VOLUMES
The acetone-water extract of Hexachlamys edulis (Myrtaceae) inhibited the enzyme xanthine oxidase (XO) in vilro. Bioassay-guided isolation led to the gallic acid ester in 2" of myricitrin (desmanthin-1), (-)-epigallocatechin-3-0-gallate (EGG) and pentagalloylglucose as the main XO inhibitors of H. e
A series (C1-C12) of alkyl gallates was examined for their effects on the activity of xanthine oxidase. Octyl (C8), decyl (C10), and dodecyl (C12) gallates competitively inhibited uric acid formation generated by xanthine oxidase, and the inhibition increased upon increasing the alkyl chain length.