Xanthine oxidase inhibitors in the management of gout
β Scribed by James B. Wyngaarden
- Publisher
- John Wiley and Sons
- Year
- 1965
- Tongue
- English
- Weight
- 421 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0004-3591
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π SIMILAR VOLUMES
## Abstract ## Objective Gout affects βΌ1β2% of the American population. Current options for treating hyperuricemia in chronic gout are limited. The purpose of this study was to assess the safety and efficacy of febuxostat, a nonpurine selective inhibitor of xanthine oxidase, in establishing normal
ty of brolxomine hyr!rocfiioride was investigated t healthy male volunteers were g i x n Tingle peroral r 'hy'rochloride after overnight fasting or a fpt-a:d proteiniich breakfast Mean ( : b SL)) areas under the plasma concentration-time curves (AUC) were 9 -5 6 (2\*j5)prm11 h when g i e n to he fas