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X-ray structure of antistasin at 1.9 Å resolution and its modelled complex with blood coagulation factor Xa

✍ Scribed by Lapatto, Risto (author);Krengel, Ute (author);Schreuder, Herman A. (author);Arkema, Anita (author);De Boer, Bijtske (author);Kalk, Kor H. (author);Hol, Wim G.J. (author);Grootenhuis, Peter D.J. (author);Mulders, John W.M. (author);Dijkema, Rein (author);Theunissen, Henri J.M. (author);Dijkstra, Bauke W. (author)


Book ID
111744977
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
618 KB
Volume
16
Category
Article
ISSN
0261-4189

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An acidic phospholipase A 2 (PLA 2 ) isolated from Bothrops jararacussu snake venom was crystallized with two inhibitors: a-tocopherol (vitamin E) and p-bromophenacyl bromide (BPB). The crystals diffracted at 1.45-and 1.85-A ˚resolution, respectively, for the complexes with a-tocopherol and p-bromop