𝔖 Bobbio Scriptorium
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X-ray diffraction as a tool in the path from the design of an active pharmaceutical ingredient to the tablet on the shelf

✍ Scribed by Bacchi, Alessia


Book ID
119956550
Publisher
Springer Milan
Year
2012
Weight
522 KB
Volume
24
Category
Article
ISSN
1120-6349

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The antiviral compound, 2-amino-6-(4-methoxyphenylthio)-9-[2-(phosphonomethoxy)ethyl]purine bis(2,2,2-trifluoroethyl)ester (MCC-478), can exist in several anhydrous polymorphic forms and also as a hemihydrate. The XRD patterns of the tablets, containing each form of the active pharmaceutical ingredi