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X-linked hypohidrotic ectodermal dysplasia: DNA probe linkage analysis and gene localization

✍ Scribed by A. Clarke; M. Sarfarazi; N. S. T. Thomas; K. Roberts; P. S. Harper

Publisher
Springer
Year
1987
Tongue
English
Weight
271 KB
Volume
75
Category
Article
ISSN
0340-6717

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EDA (ectodermal dysplasia, anhidrotic) is an X-linked recessive disorder characterized by hypohidrosis, hypoor anodontia, and hypotrichosis. A possible linkage between the gene for EDA and a number of restriction fragment length polymorphisms (RFLPs) spread over the X chromosome was investigated in