In a 5-12 year follow-up study of 288 subjects with impaired glucose tolerance after a 100-g glucose load, 48 worsened to overt Type 2 (non-insulin-dependent) diabetes with the elevation of fasting blood glucose. The initial level of blood glucose was a major predictor of subsequent worsening to dia
Worsening to diabetes in men with impaired glucose tolerance (“borderline diabetes”)
✍ Scribed by R. J. Jarrett; H. Keen; J. H. Fuller; M. McCartney
- Publisher
- Springer
- Year
- 1979
- Tongue
- English
- Weight
- 511 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0012-186X
No coin nor oath required. For personal study only.
✦ Synopsis
Two hundred and four men with impaired glucose tolerance (borderline diabetes) discovered in a screening examination have been observed for five years and repeated tests of glucose tolerance performed. By pre-determined criteria 27 men 'worsened to diabetes' and this metabolic deterioration was not significantly influenced by treatment with carbohydrate restriction with or without a daily dose of 50 mg phenformin. Of the baseline variables measured prior to treatment allocation only the blood glucose values were significantly predictive of ultimate worsening to diabetes.
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