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WNT INHIBITORY FACTOR 1 IS INACTIVATED BY HYPERMETHYLATION AND FUNCTIONS AS A TUMOR SUPPRESSOR IN KIDNEY CANCER CELLS

✍ Scribed by Kawakami, Kazumori; Hirata, Hiroshi; Yamamura, Soichiro; Kikuno, Nobuyuki; Majid, Shahana; Saini, Sharanjot; Tanaka, Yuichiro; Kawamoto, Ken; Enokida, Hideki; Nakagawa, Masayuki; Dahiya, Rajvir


Book ID
122890197
Publisher
Lippincott Williams and Wilkins
Year
2009
Tongue
English
Weight
46 KB
Volume
181
Category
Article
ISSN
0022-5347

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Secreted frizzled-related protein-5 is e
✍ Kazumori Kawakami; Soichiro Yamamura; Hiroshi Hirata; Koji Ueno; Sharanjot Saini πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 French βš– 592 KB

## Abstract Secreted frizzled‐related protein‐5 (__sFRP‐5__) has been identified as 1 of the secreted antagonists that bind Wnt protein. However, the functional significance of __sFRP‐5__ in renal cell cancer (RCC) has not been reported. We hypothesized that __sFRP‐5__ may be epigenetically downreg