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Wnt-frizzled signaling to G-protein-coupled effectors

✍ Scribed by H.-Y. Wang; C.C. Malbon


Book ID
105757657
Publisher
Springer
Year
2004
Tongue
English
Weight
297 KB
Volume
61
Category
Article
ISSN
1420-682X

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## Abstract Wnt proteins initiate signaling by binding to seven transmembrane spanning receptors of the frizzled (Fz) family together with the members of the low‐density lipoprotein receptor‐related protein (LRP) 5 and 6. A chimera of human Wnt3 and Fz1 receptor was developed that efficiently activ