Wnt3-frizzled 1 chimera as a model to st
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Ramesh A. Bhat; Barbara Stauffer; Anthony Della Pietra; Peter V.N. Bodine
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Article
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2009
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John Wiley and Sons
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English
β 503 KB
## Abstract Wnt proteins initiate signaling by binding to seven transmembrane spanning receptors of the frizzled (Fz) family together with the members of the lowβdensity lipoprotein receptorβrelated protein (LRP) 5 and 6. A chimera of human Wnt3 and Fz1 receptor was developed that efficiently activ