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Non-canonical wnt signals antagonize and canonical wnt signals promote cell proliferation in early kidney development

✍ Scribed by Kyle E. McCoy; Xiaolan Zhou; Peter D. Vize


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
578 KB
Volume
240
Category
Article
ISSN
1058-8388

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## Background Phosphatidylinositol (PI) 3-kinase is activated by a variety of growth factor receptors and the PI 3-kinase/Akt signaling pathway is a key regulator of cell proliferation and survival. The downstream targets of PI 3-kinase/Akt signaling include direct regulators of cell cycle progress