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Wnt-3a overcomes β-amyloid toxicity in rat hippocampal neurons

✍ Scribed by Alejandra R Alvarez; Juan A Godoy; Karin Mullendorff; Gonzalo H Olivares; Miguel Bronfman; Nibaldo C Inestrosa

Book ID
116980969
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
637 KB
Volume
297
Category
Article
ISSN
0014-4827

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## Abstract Astrocytosis is a common feature of amyloid plaques, the hallmark of Alzheimer's disease (AD), along with activated microglia, neurofibrillary tangles, and β‐amyloid (βA) deposition. However, the relationship between astrocytosis and neurodegeneration remains unclear. To assess whether