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Will multimodality therapy solve the enigma of long-term survival for squamous cell carcinoma of the esophagus?

✍ Scribed by Joseph Locicero III


Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
514 KB
Volume
9
Category
Article
ISSN
8756-0437

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✦ Synopsis


Abstract

Squamous carcinoma of the esophagus is a disease with a poor prognosis which fortunately occurs seldom in the United States. Because patients present with more advanced disease here, surgical therapy has not equaled results reported from Asia. Although, claims of equality have appeared in the literature, radiation therapy alone has not been very effective for this disease. There are a myriad of small reports which extol a variety of combined approaches. Based upon a review of these series it is obvious that a Phase III trial is required to establish the best multimodality therapy for management of squamous carcinoma of the esophagus. Components of such a trial are reviewed and suggestions are made for design and reporting of such a trial.


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