Will multimodality therapy solve the enigma of long-term survival for squamous cell carcinoma of the esophagus?
β Scribed by Joseph Locicero III
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 514 KB
- Volume
- 9
- Category
- Article
- ISSN
- 8756-0437
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
Squamous carcinoma of the esophagus is a disease with a poor prognosis which fortunately occurs seldom in the United States. Because patients present with more advanced disease here, surgical therapy has not equaled results reported from Asia. Although, claims of equality have appeared in the literature, radiation therapy alone has not been very effective for this disease. There are a myriad of small reports which extol a variety of combined approaches. Based upon a review of these series it is obvious that a Phase III trial is required to establish the best multimodality therapy for management of squamous carcinoma of the esophagus. Components of such a trial are reviewed and suggestions are made for design and reporting of such a trial.
π SIMILAR VOLUMES
## Between 1965 and 1981, 119 patients with squamous cell carcinoma of the esophagus were treated with radiation therapy with curative intent. Radiation was employed in combination with surgery and delivered pre-and/or postoperatively in 20 patients (17 %). The remainder received radiotherapy alon
Endoscopic laser therapy provides effective symptomatic palliation for patients with squamous cell carcinoma of the esophagus. To investigate whether this treatment also prolongs survival, a retrospective case-control study was performed. Ten patients with squamous cell carcinoma of the esophagus, d