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Widespread expression of Agouti-related protein (AGRP) in the chicken: a possible involvement of AGRP in regulating peripheral melanocortin systems in the chicken

✍ Scribed by Sakae Takeuchi; Kiyoshi Teshigawara; Sumio Takahashi


Book ID
117350515
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
634 KB
Volume
1496
Category
Article
ISSN
0167-4889

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✍ Andrzej M. Wilczynski; Christine G. Joseph; Carrie Haskell-Luevano 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 264 KB

## Abstract Agouti‐related protein (AGRP) is an endogenous antagonist of the melanocortin‐3 and ‐4 (MC3R and MC4) G‐protein coupled receptors. The 87–132 amino acid C‐terminal domain of hAGRP possesses five disulfide bridges and a well‐defined three‐dimensional structure that displays full biologic