Why does the neuronal firing rate increase with a greater injected current?

High-frequency stimulation of the subtha

High-frequency stimulation of the subthalamic nucleus increases pallidal neuronal firing rate in a patient with Parkinson's disease

✍ René Reese; Frank Steigerwald; Monika Pötter; Jan Herzog; Günther Deuschl; Jens 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 245 KB

FIG. 1. (A) Location of neuronal recording sites in a sagittal projection onto the Schaltenbrand Wahren atlas at the average laterality of 22 mm. (B) Mean firing rates in GPi and GPe are increased after STN-HFS. Box plots show median (line within the box) as well as 10, 25, 75, and 90th percentiles