For cross-presentation immature dendritic cells (DC) require enhanced antigen (Ag) uptake and a maturation signal to prime for MHC class I-restricted CTL responses in vivo. While immunostimulatory CpG-DNA provides, via TLR9, the maturation signal, CpG-DNA linked to Ag augments cellular Ag uptake. In
โฆ LIBER โฆ
Whole lymphoma B cells allow efficient cross-presentation of antigens by dendritic cells
โ Scribed by Manches, O.; Lui, G.; Manches, O.; Lui, G.; Molens, Jp; Sotto, Jj; Chaperot, L.; Plumas, J.
- Book ID
- 122218059
- Publisher
- Informa plc
- Year
- 2008
- Tongue
- English
- Weight
- 377 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1465-3249
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