The prediction ability of a test to detect genotoxic been assayed in both deficient repair conditions. As activity may be increased, at least from a theoretical in the w/w / and mwh/flr 3 SMARTs, the results obpoint of view, by carrying it out under deficient re-tained with the w i assay show that the use of deficient pair conditions. The white-ivory (w i ) assay of Drorepair strains does not improve the detection of genosophila melanogaster is a somatic mutation and re-toxic effects. However, the utilization of these deficombination test (SMART) that essentially differs cient repair strains has been shown to be a useful from other SMARTs by the endpoints that can be tool in mechanistic studies. In fact, it seems that the detected. In this article, we study the consequences, nucleotide excision repair system mainly eliminates with the w i assay, of the introduction of two muta-some spontaneous and chemically-induced damages tions, mus201 and mei-41, which produce defi-involved in the reversion of w i , whereas the repair ciency in two different repair mechanisms: the nu-system deficient in mei-41 flies is partly necessary to cleotide excision repair system and in a G2/M cell-recover revertant w i spots.