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Which agonist properties are important for the activation of 5-HT3A receptors?

✍ Scribed by Meiboom, M.F.; Barann, M.; Witten, S.; Groeneveld, K.; Urban, B.W.


Book ID
122205229
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
1006 KB
Volume
1828
Category
Article
ISSN
0005-2736

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Several substituted 2-pyridazinyl benzoxazole derivatives (VII), (VIII) and (IX) are prepared and evaluated for their utility as 5-HT 3 receptor agonists. A detailed structure-activity relationship study is presented. The most promising results are obtained for the derivatives (VIIa), (VIId) and (VI