## Abstract Mutation of tumor suppressor p53 gene gains new function in regulation of DNA damageβinduced apoptotic response in tumor cells, which may lead to a poor response in cancer chemotherapy and radiotherapy. Transfection of mutant p53 (R175H) to p53βnull osteosarcoma Saosβ2 cells suppressed
β¦ LIBER β¦
When mutants gain new powers: news from the mutant p53 field
β Scribed by Brosh, Ran; Rotter, Varda
- Book ID
- 109948378
- Publisher
- Nature Publishing Group
- Year
- 2009
- Tongue
- English
- Weight
- 467 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1474-1776
- DOI
- 10.1038/nrc2693
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