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What is the role of HLA-B27 in spondyloarthropathies?

✍ Scribed by Anthoula Chatzikyriakidou; Paraskevi V. Voulgari; Alexandros A. Drosos


Book ID
113482414
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
217 KB
Volume
10
Category
Article
ISSN
1568-9972

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The pathogenetic aspects of spondyloarth
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The association of HLA-B27 and seronegative spondyloarthropathies, especially ankylosing spondylitis has been known for almost two decades. The spontaneous development of spondyloarthropathy like joint disease in HLA-B27 transgenic rats verifies the suspicion that the HLA-B27 antigens are directly r