What Is the Correct Value for the Brain-Blood Partition Coefficient for Water?
✍ Scribed by Herscovitch, Peter; Raichle, Marcus E.
- Book ID
- 109869673
- Publisher
- Nature Publishing Group
- Year
- 1985
- Tongue
- English
- Weight
- 261 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0271-678X
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It is shown that log P values for water-alkane or water-cyclohexane partitions, and the corresponding Delta log P values when used as descriptors for blood-brain distribution, as log BB, yield equations with very poor correlation coefficients but very good standard deviations, S from 0.25 to 0.33 lo
## Abstract We describe the use of relative proton density imaging to obtain spatially resolved measurements of the brain:blood partition coefficient for water. Values of relative proton density and apparent‐T1 were calculated by performing a multidimensional nonlinear least squares fit of progress