Water–solvent partition coefficients and
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Abraham, Michael H. (author);Acree, William E. (author);Leo, Albert J. (author);
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Article
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2010
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John Wiley and Sons Inc.
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English
⚖ 157 KB
It is shown that log P values for water-alkane or water-cyclohexane partitions, and the corresponding Delta log P values when used as descriptors for blood-brain distribution, as log BB, yield equations with very poor correlation coefficients but very good standard deviations, S from 0.25 to 0.33 lo