What is Alpha Crystallin?
β Scribed by Spector, Abraham; Li, Lu-Ku; Meretsky, Dianne; Augusteyn, Robert
- Book ID
- 127166373
- Publisher
- Elsevier Science
- Year
- 1971
- Tongue
- English
- Weight
- 390 KB
- Volume
- 71
- Category
- Article
- ISSN
- 0002-9394
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π SIMILAR VOLUMES
A major component of the soluble fraction of rat heart is a homopolymer (Mr about 400-650 k) of a small protein (Mr about 20 k). This cardiac protein, which is highly homologous to alpha-B-crystallin, was isolated in its native state and visualized by electron microscopy. A homogeneous population of
Rat hearts were perfused in the working heart or Langendorff mode and then subjected to total normothermic ischemia. The content of alpha-crystallin in the water soluble protein fraction obtained from these hearts diminished in a time-dependent manner during ischemia. The protein was recovered in th