‘Purity’ of Alpha-Crystallin
✍ Scribed by BLOEMENDAL, H.; BONT, W. S.; JONGKIND, J. F.; WISSE, J. H.
- Book ID
- 109619715
- Publisher
- Nature Publishing Group
- Year
- 1962
- Tongue
- English
- Weight
- 360 KB
- Volume
- 193
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/193437a0
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
A major component of the soluble fraction of rat heart is a homopolymer (Mr about 400-650 k) of a small protein (Mr about 20 k). This cardiac protein, which is highly homologous to alpha-B-crystallin, was isolated in its native state and visualized by electron microscopy. A homogeneous population of
Rat hearts were perfused in the working heart or Langendorff mode and then subjected to total normothermic ischemia. The content of alpha-crystallin in the water soluble protein fraction obtained from these hearts diminished in a time-dependent manner during ischemia. The protein was recovered in th