Weighing the evidence for structure: electrospray ionization mass spectrometry of proteins
β Scribed by Carol V Robinson; Sheena E Radford
- Book ID
- 114328882
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 559 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0969-2126
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π SIMILAR VOLUMES
## Abstract Membrane proteins drive and mediate many essential cellular processes making them a vital section of the proteome. However, the amphipathic nature of these molecules ensures their detailed structural analysis remains challenging. A versatile procedure for effective electrosprayβionizati
## Abstract Electrospray ionization mass spectrometry (ESIβMS) has proven to be a useful tool for examining noncovalent complexes between proteins and a variety of ligands. It has also been used to distinguish between denatured and refolded forms of proteins. Surfactants are frequently employed to
A novel method of detecting proteins at low concentration based upon electrospray ionizationαmass spectrometry and gas-phase proton transfer reactions is described. In this technique the signal that is spread over a broad mass range due to the distribution of multiply charged ions generated in elect