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Weekly administration of topotecan–paclitaxel as second-line treatment in ovarian cancer

✍ Scribed by G. P. Stathopoulos; N. A. Malamos; G. Aravantinos; S. Rigatos; Ch. Christodoulou; J. Stathopoulos; D. Skarlos


Publisher
Springer
Year
2006
Tongue
English
Weight
255 KB
Volume
60
Category
Article
ISSN
0344-5704

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## Abstract ## BACKGROUND The high incidence of dose‐limiting myelosuppresion using the U.S. Food and Drug Administration‐approved topotecan dose of 1.5 mg/m^2^ for 5 days every 3 weeks may have limited its utility in the treatment of patients with epithelial ovarian carcinoma. The objective of th