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Weekly administration of topotecan and paclitaxel in pretreated advanced cancer patients: a phase I/II study

โœ Scribed by George P. Stathopoulos; Sotiris K. Rigatos; Christos Christodoulou; Nikos A. Malamos; Filippos Deliyiannis; John G. Stathopoulos; Dimosthenis V. Skarlos

Publisher
Springer
Year
2004
Tongue
English
Weight
182 KB
Volume
54
Category
Article
ISSN
0344-5704

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A phase I study of a weekly schedule of
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โœ Wallace Akerley; Ritesh Rathore; Neil Ready; Louis Leone; William Sikov; Howard ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 64 KB ๐Ÿ‘ 2 views

## Background: We conducted a phase i study of weekly paclitaxel (p) and carboplatin (c) in patients with advanced malignancies to determine the maximum tolerated dose (mtd) of this combination. ## Methods: Dose levels were escalated independently for patients with and without previous chemothera