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Web alert Folding and binding Protein-nucleic acid interactions

✍ Scribed by PhilipE Bourne; Judith Murray-Rust; JeremyH Lakey

Book ID: 117656126
Publisher: Elsevier Science
Year: 1997
Tongue: English
Weight: 109 KB
Volume: 7
Category: Article
ISSN: 0959-440X
DOI: 10.1016/s0959-440x(97)80017-6

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## Abstract The negatively charged phosphates of nucleic acids are often paired with positively charged residues upon binding proteins. It was thus counter‐intuitive when previous Poisson–Boltzmann (PB) calculations gave positive energies from electrostatic interactions, meaning that they destabili