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Folding and binding: Protein–nucleic acid interactions: Web alert

✍ Scribed by Philip E Bourne; Judith Murray-Rust; Jeremy H Lakey

Book ID: 114314912
Publisher: Elsevier Science
Year: 2000
Tongue: English
Weight: 37 KB
Volume: 10
Category: Article
ISSN: 0959-440X
DOI: 10.1016/s0959-440x(99)90023-4

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## Abstract The negatively charged phosphates of nucleic acids are often paired with positively charged residues upon binding proteins. It was thus counter‐intuitive when previous Poisson–Boltzmann (PB) calculations gave positive energies from electrostatic interactions, meaning that they destabili