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WAY 120,491 activates ATP-sensitive potassium channels in rat tail artery

✍ Scribed by Philip B. Furspan

Book ID
115888178
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
302 KB
Volume
223
Category
Article
ISSN
0014-2999

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Modulation of ATP-sensitive potassium ch
Modulation of ATP-sensitive potassium channel activity by flash-photolysis of β€˜caged-ATP’ in rat heart cells
✍ C. G. Nichols; E. Niggli; W. J. Lederer πŸ“‚ Article πŸ“… 1990 πŸ› Springer 🌐 English βš– 355 KB

We have used 'caged-ATP' to investigate the kinetic behavior of KATP channels in ventricular cells from rat heart. In whole cells, loaded with 'caged-ATP', an increase of intracellular [ATP] following a UV light flash produced a decrease of KATP channel current that was too slow (tau approximately 3