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Water-Soluble Phosphinothiols for Traceless Staudinger Ligation and Integration with Expressed Protein Ligation

✍ Scribed by Tam, Annie; Soellner, Matthew B.; Raines, Ronald T.


Book ID
111977900
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
519 KB
Volume
129
Category
Article
ISSN
0002-7863

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The development of rapid radiolabeling techniques under mild reaction conditions involving the shortlived positron emitter fluorine-18 remains a special challenge in organic PET chemistry. This work describes a novel and facile application of the traceless Staudinger ligation as a mild and versatile