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Water extracts of cinnamon and clove exhibits potent inhibition of protein glycation and anti-atherosclerotic activity in vitro and in vivo hypolipidemic activity in zebrafish

✍ Scribed by Seori Jin; Kyung-Hyun Cho

Book ID
116463753
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
611 KB
Volume
49
Category
Article
ISSN
0278-6915

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Analogues of staurosporine were synthesized and their ability to inhibit protein kinases was examined. Staurosporine is a potent but non-selective inhibitor of in vitro protein kinase C (PKC) activity (K5, 6.0 nn). The derivative CGP 41 25 I had reduced PKC activity with an IC,, of 50 nn but showed