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W1936 Celecoxib-Induced Apoptosis Is Enhanced By Inhibition of Autophagy in Human Colon Cancer Cells

✍ Scribed by Huang, Shengbing; Sinicrope, Frank A.

Book ID: 123189892
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 49 KB
Volume: 136
Category: Article
ISSN: 0016-5085
DOI: 10.1016/S0016-5085(09)63495-8

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## Abstract Although it is often assumed that the antitumor effects of nonsteroidal anti‐inflammatory drugs (NSAIDs) are due to inhibition of cyclooxgenase (COX) activity, specifically COX‐2, there is accumulating evidence that COX‐2 independent mechanisms can also play an important role. Studies w