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W01.29 Influence of genetic variants on the activity of platelet-activating-factor acetylhydrolase (PAF-AH)

✍ Scribed by Hoffmann, M.; Simon, M.; Winkelmann, B.; Boehm, B.; Maerz, W.; Winkler, K.


Book ID
118632424
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
151 KB
Volume
5
Category
Article
ISSN
1567-5688

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Racemic analogues of platelet-activating factor and its lyso derivatives have been prepared in which one methyl of the trimethylammonium group has been replaced by ethyl, propyl, allyl, or carboxymethylene. The influence of chemical modification on the biological activity was assessed by measuring p