Activation of LKB1-Akt pathway independe
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Nuria MartΓnez-LΓ³pez; Marta Varela-Rey; David FernΓ‘ndez-Ramos; Ashwin Woodhoo; M
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Article
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2010
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John Wiley and Sons
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English
β 843 KB
LKB1, originally considered a tumor suppressor, plays an important role in hepatocyte proliferation and liver regeneration. Mice lacking the methionine adenosyltransferase (MAT) gene MAT1A exhibit a chronic reduction in hepatic S-adenosylmethionine (SAMe) levels, basal activation of LKB1, and sponta