𝔖 Bobbio Scriptorium
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VP16-213 and podophyllotoxin

✍ Scribed by John D. Loike


Publisher
Springer
Year
1982
Tongue
English
Weight
882 KB
Volume
7
Category
Article
ISSN
0344-5704

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The fluorination of the antitumour agents VP 16-213 and podophyllotoxin using ['sF]acetyl hypofluorite is described. Overall labeling yields of 10% and 20% respectively were obtained. The F-atom is found to be introduced into the E-moiety of the compounds, apparently without unwanted conformational

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