Voltammetric determination of boron in plasma using Beryllon(III) as a ligand

✍ Scribed by L. Thunus

• Publisher: Elsevier Science
• Year: 1996
• Tongue: English
• Weight: 405 KB
• Volume: 318
• Category: Article
• ISSN: 0003-2670
• DOI: 10.1016/0003-2670(95)00462-9

✦ Synopsis

An alternative, sensitive method to inductively coupled plasma and neutron activation mass spectrometry for the evaluation of human boron plasma levels was investigated. Adsorptive stripping voltammetry with a differential pulse modulation was chosen. UV digestion was used to remove organic matter. Beryllon(II1) was used as the ligand for boron; the best conditions of the method were found to be: 0.05 M HOAc/0.025 M NH,OAc buffer supporting electrolyte; 7 x 1O-5 M Beryllon(II1); -0.250 V accumulation potential (vs. Ag/AgCl/sat. KCl); 200 mV/s-' sweep rate. The linear range for boron determination was 0 to 20 pg l-', with a correlation coefficient of 0.9997 (n = 8). Blood samples from healthy female volunteers (mean 59 years: range 49-68 years) were analyzed. A boron plasma level of 35.00 f 6.53 pg 1-l was found, which agrees with the literature values of the last five years.