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Voltage-gated sodium channels activity promotes cysteine cathepsins-dependent invasiveness of human cancer cell lines

✍ Scribed by L. Gillet; S. Roger; P. Besson; J. Gore; P. Bougnoux; F. Lecaille; G. Lalmanach; J.Y. Le Guennec


Book ID
119598677
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
90 KB
Volume
6
Category
Article
ISSN
1359-6349

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## BACKGROUND. Although ion channels are known to contribute to a variety of basic cellular behaviors involved in the metastatic cascade, their role in metastasis per se has only recently been questioned. The hypothesis tested was whether K channels were different between strongly metastatic PC-3