Vitamin K1 amplification of benzo(a)pyrene metabolism in chick embryos
โ Scribed by S.C. Dogra; L.G. Israels
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- English
- Weight
- 241 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0020-711X
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๐ SIMILAR VOLUMES
With the object of establishing a test for specific locus mutations in the somatic cells of mice, the effect of benzo(a)pyrene on the developing pigment cells of mouse embryos was investigated. Embryos were heterozygous for genes affecting coat-colour so that mutations could be scored as spots on th
## Abstract The metabolism of tritiated benzo[a]pyrene (B[a]P) by primary mouse embryo cells in culture was studied. At concentrations of B[a]P in the medium below about 2โ3 mฮผ moles/ml, metabolism was exponential with time, but at higher concentrations a period of rapid metabolism was followed by