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Interaction between vitamin K3 and benzo(a)pyrene metabolism in uninduced microsomes

✍ Scribed by Janusz Z. Byczkowski; Teresa Gessner


Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
594 KB
Volume
19
Category
Article
ISSN
0020-711X

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We have used the human hepatoma cell line, Hep G2, to examine the ability of hormones and xenobiotics to modulate the hepatic induction of benzo(a)pyrene hydroxylase and epoxide hydrolase. Hep G2 cells were cultured in Eagle's Minimum Essential Medium supplemented with 10% fetal calf serum. 3-Methyl