Vitamin E and glutathione as endogenous protective agents against oxidative heartdamage
β Scribed by R. Julicher; L. Sterrenberg; A. Bast; J. Koomen; J. Noordhoek
- Book ID
- 119440718
- Publisher
- Elsevier Science
- Year
- 1984
- Tongue
- English
- Weight
- 79 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0022-2828
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Oxidized LDL is taken up by the macrophage scavenger receptor and leads to lipid laden foam cells, which are characteristic constituents of early atherosclerotic lesions. Oxidation of LDL is a lipid peroxidation process, in which the PUFAs contained in the LDL lipids (on average 1200 molecules PUFAs
Free radicals can disturb the intracellular homeostasis by either modification of essential free sulfhydryl groups or by inducing lipid peroxidation. The damage provoked by oxidation of sulfhydryl groups might be reversible but the damage induced by the process of lipid peroxidation is probably not