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Vitamins C and E protect isolated cardiomyocytes against oxidative damage

✍ Scribed by T Rinne; E Mutschler; G Wimmer-Greinecker; A Moritz; H.G Olbrich


Book ID
117351467
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
484 KB
Volume
75
Category
Article
ISSN
0167-5273

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Oxidized LDL is taken up by the macrophage scavenger receptor and leads to lipid laden foam cells, which are characteristic constituents of early atherosclerotic lesions. Oxidation of LDL is a lipid peroxidation process, in which the PUFAs contained in the LDL lipids (on average 1200 molecules PUFAs