Vitamin D3: Synthesis of seco C-9,11,21-trisnor-17-Methyl-1α,25-dihydroxyvitamin D3 Analogues.
✍ Scribed by Yusheng Wu; Katrien Sabbe; Pierre De Clercq; Maurits Vandewalle; Roger Bouillon; Annemieke Verstuyf
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 41 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0931-7597
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Copper-Mediated Alkylation of Vitamin D C-Ring. Synthesis of C11-Functionalized 1α,25-Dihydroxyvitamin D3. -The functionalization of C-11 of CD-ring fragments of vitamin D3, e.g. (I), with organocopper reagents is studied. The application results in an efficient, convergent synthesis of the calcitr
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