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Vitamin D receptor activity and prevention of colonic hyperproliferation and oxidative stress

✍ Scribed by E Kállay; P Bareis; E Bajna; S Kriwanek; E Bonner; S Toyokuni; H.S Cross


Book ID
117449965
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
165 KB
Volume
40
Category
Article
ISSN
0278-6915

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## Abstract The activity of β‐catenin, commonly dysregulated in human colon cancers, is inhibited by the vitamin D receptor (VDR), and this mechanism is postulated to explain the putative anti‐cancer activity of vitamin D metabolites in the colon. We investigated the effect of a common __Fok__I res