Malformations in offspring of diabetic r
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Sim�n, C. Martin; Gittenberger-De Groot, Adriana C.; Wisse, Bert; Eriksson, Ulf
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Article
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2000
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John Wiley and Sons
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English
⚖ 816 KB
## Background: We have previously reported on a malformation-prone Sprague-Dawley rat substrain (U), which presents a high frequency of micrognathia in the offspring of diabetic mothers. This malformation is related to impaired development of the cranial neural crest cells (NCC); the defect may be